Evaluation of qSOFA and variation of hematochemical profile in cats naturally infected with feline panleukopenia virus

Evaluation of qSOFA and variation of hematochemical profile in cats naturally infected with feline panleukopenia virus

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Feline panleukopenia (FP) is a fatal viral disease that predisposes cats to sepsis and organ failure.Owing to a wide variety of clinical findings, hematochemical examinations are significant for the determination of early signs of disease-related complications.The aim of this study is to investigate the diagnostic efficacy of certain hematochemical parameters together with quick Sepsis-related Organ Failure Assessment (qSOFA) in cats with FP.A total of 10 healthy and 30 panleukopenic cats were included in this study.Physical examinations revealed that the body temperature was highest in septic panleukopenic Handheld Vacuum Brush Motor cats (p < 0.

009) and they had higher qSOFA scores (p = 0.000).Hemogram analysis revealed that leukocyte, lymphocyte, granulocyte, erythrocyte, and hemoglobin levels were lower in non-septic panleukopenic cats compared with the healthy ones (p < 0.030).Also, monocyte and mean corpuscular hemoglobin levels were lower in septic ones (p < 0.

048).Serum biochemistry profiling revealed higher blood urea nitrogen, creatinine, alanine aminotransferase, lactate dehydrogenase, total bilirubin, and C-reactive protein levels in panleukopenic cats (p < 0.033).As a result, it was concluded that although the qSOFA is AMPK Activator not sufficient to distinguish sepsis in cats, unlike dogs, in order to achieve a positive clinical outcome, when evaluated together with hematochemical variables, it may help in making early diagnosis of FP-related complications.